Research Interests

Over the years, Dieter Seebach has summarized the results obtained in his research group in review articles. The terms, concepts, techniques, and methodologies introduced and the total syntheses achieved include:

reactivity umpolung (of carbonyl compounds, amines, imines and nitroolefins) Download75 (PDF, 1.5 MB), Download153 (PDF, 352 KB), Download156 (PDF, 1.5 MB), Download212 (PDF, 1.2 MB), Download224 (PDF, 2.2 MB)
reactivity of nitroaliphatic compounds (Li₂-nitronates, stereoselective nitroaldol additions) Download153 (PDF, 352 KB), Download229 (PDF, 589 KB), Download545 (PDF, 282 KB), Download548 (PDF, 243 KB), Download549 (PDF, 230 KB), Download550 (PDF, 462 KB), Download856 (PDF, 1.8 MB)
use of organosulfur and – selenium compounds in organic synthesis (DownloadPULI No.99) Download28 (PDF, 1 MB), Download72 (PDF, 676 KB), Download74 (PDF, 221 KB), Download108 (PDF, 954 KB), Download131 (PDF, 2.7 MB)
use of Downloadmicroorganism and enzymes as reagents (PDF, 93 KB) for organic synthesis Download281 (PDF, 116 KB), Download416 (PDF, 209 KB), Download471 (PDF, 106 KB), Download803 (PDF, 297 KB),Download822 (PDF, 259 KB)
sterically protected, but electronically effective functional groups (DownloadSPEEF (PDF, 80 KB)) Download244 (PDF, 1.1 MB), Download288 (PDF, 1.3 MB), Download309 (PDF, 1 MB), Download724 (PDF, 431 KB)
the LiX effect and reactivity of organolithium compounds Download279 (PDF, 3.7 MB), Download386 (PDF, 3.4 MB), Download528 (PDF, 18.3 MB)
reactivity and selectivity of organotitanium compounds Download241 (PDF, 1.2 MB), Download251 (PDF, 719 KB), Download391 (PDF, 2.3 MB), Download836 (PDF, 400 KB),
self-regeneration of stereogenic centers (SRS) (DownloadPULI No. 339), Download576 (PDF, 4.7 MB)
synthetic applications of Downloadelectrolysis (PDF, 62 KB) in enantioselective syntheses Download87 (PDF, 287 KB), Download328 (PDF, 252 KB), Download338 (PDF, 493 KB), Download344 (PDF, 414 KB), Download376 (PDF, 624 KB), Download393 (PDF, 1.6 MB), Download576 (PDF, 4.7 MB)
DownloadTADDOLs (PDF, 104 KB), a true chiral-auxiliary system (DownloadPULI No. 696) Download678 (PDF, 1.5 MB), Download724 (PDF, 431 KB) , Download792 (PDF, 1.3 MB), Download849 (PDF, 655 KB), Download850 (PDF, 628 KB), Download851 (PDF, 680 KB)
chemistry of Downloadfluoro-organic compounds (PDF, 99 KB) Download276 (PDF, 706 KB), Download316 (PDF, 589 KB), Download318 (PDF, 240 KB), Download451 (PDF, 1.7 MB), Download808 (PDF, 1.3 MB), Download844 (PDF, 951 KB)
immobilization of chiral ligands by dendritic cross-linking in polystyrene and by attachment to controlled pore glass (CPG) Download678 (PDF, 1.5 MB), Download712 (PDF, 765 KB), Download713 (PDF, 664 KB), Download743 (PDF, 484 KB)
chiral dendrimers Download577 (PDF, 391 KB), Download593 (PDF, 2.6 MB), Download617 (PDF, 940 KB)
polymers and oligomers of 3-hydroxybutanoate (DownloadPHB (PDF, 125 KB), OHB) - ion-channel-forming biomacromolecules Download480 (PDF, 3 MB),Download556 (PDF, 11.5 MB), Download595 (PDF, 344 KB), Download640 (PDF, 1.1 MB), Download720 (PDF, 71 KB)
chemical, biological and biomedical investigations of peptides consisting of homologated proteinogenic amino acids (Downloadβ- and γ-peptides (PDF, 229 KB) )Download596 (PDF, 475 KB), Download739 (PDF, 854 KB),Download763 (PDF, 1019 KB), Download767 (PDF, 9.6 MB), Download768 (PDF, 2.2 MB), Download775 (PDF, 1.2 MB), Download787 (PDF, 649 KB), Download815 (PDF, 945 KB), Download819 (PDF, 973 KB), Download861 (PDF, 987 KB)
organocatalysis (DownloadOC (PDF, 83 KB)) Download801 (PDF, 1.6 MB), Download817 (PDF, 2.1 MB), Download820 (PDF, 1 MB), Download823 (PDF, 1.7 MB), Download830 (PDF, 1.2 MB), Download834 (PDF, 2.4 MB), Download840 (PDF, 1.3 MB), Download848 (PDF, 695 KB), Download851 (PDF, 680 KB), Download856 (PDF, 1.8 MB), Download859 (PDF, 248 KB)
total syntheses of various Downloadnatural products (PDF, 520 KB) Download271 (PDF, 243 KB), Download331 (PDF, 607 KB), Download358 (PDF, 252 KB), Download362 (PDF, 309 KB), Download405 (PDF, 285 KB), Download448 (PDF, 279 KB)
reactions at temperatures below –80°C Download240 (PDF, 129 KB), Download253 (PDF, 3.1 MB)
DMPU - a non-toxid substitute of HMPA Download543 (PDF, 575 KB)
terms:
EPC synthesis (enantiomerically pure compounds) Download186 (PDF, 648 KB)
like/unlike specification of the stereochemical course of reactions Download233 (PDF, 589 KB)
the diarylmethanol effect (DownloadTADDOL (PDF, 104 KB), DownloadDIOZ (PDF, 72 KB)) Download678 (PDF, 1.5 MB), Download724 (PDF, 431 KB), Download747 (PDF, 274 KB)
discovery of the β-peptide cleaving enzyme BapA (DownloadBapA (PDF, 56 KB)) Download782 (PDF, 157 KB), Download794 (PDF, 868 KB), Download803 (PDF, 297 KB), Download835 (PDF, 333 KB), Download852 (PDF, 1.6 MB), Download853 (PDF, 636 KB)
General article on the future of Organic Synthesis Download421 (PDF, 3.5 MB)